# UIS example for the crq Peng-Hwang method. #estimate the Peng and Huang model using log(TIME) AFT specification if(requireNamespace("survival", quietly = TRUE)) { data(uis) Surv <- survival::Surv fit <- crq(Surv(log(TIME), CENSOR) ~ ND1 + ND2 + IV3 + TREAT + FRAC + RACE + AGE * SITE, method = "Portnoy", data = uis) Sfit <- summary(fit,1:19/20) PHit <- survival::coxph(Surv(TIME, CENSOR) ~ ND1 + ND2 + IV3 + TREAT + FRAC + RACE + AGE * SITE, data = uis) plot(Sfit, CoxPHit = PHit) formula <- ~ ND1 + ND2 + IV3 + TREAT + FRAC + RACE + AGE * SITE -1 X <- data.frame(model.matrix(formula,data=uis)) newd <- as.list(apply(X,2,median)) pred <- predict(fit, newdata=newd, stepfun = TRUE) plot(pred,do.points=FALSE,xlab = expression(tau), ylab = expression(Q(tau)), lwd = 1.5, main= "Quantiles at Median Covariate Values") plot(rearrange(pred),add=TRUE,do.points=FALSE,col.vert ="red", col.hor="red") legend(.10,10,c("Raw","Rearranged"),lty = rep(1,2),col=c("black","red")) }