Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders  in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first  publication  to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. RA2_R00004_Proteomics_2024_06_03

Summary

The proteomics core facility at the Genome Sciences Centre assists a diverse base of collaborators and clients to characterize and quantify the changes in  the proteome that drive disease, particularly in cancer. Our work is multidisciplinary in nature, utilizing state-of-the-art mass spectrometry instrumentation and novel methodologies to identify and validate proteins that can act as therapeutic targets and biomarkers for the translation of genomic information into clinical practice.

The Research Assistant of the proteomics core facility will primarily be responsible for preparation of clinical and research samples for proteomic analysis. The position is within a multidisciplinary team that supports fostering scientific and personal development and learning within individuals and the group. The Research Assistant works together with the Facility Manager, staff scientists, and students to plan, coordinate, conduct and report on mass spectrometry based research projects. The successful candidate will have exemplary wet lab skills , organization, communication, and teamwork and be excited to work in a collaborative, multidisciplinary setting.

Duties

Administrative

• Maintaining data logs of samples analyzed and instrument use
• Liaising with collaborators to coordinate sample submission and communicating results
• Communicating and maintaining contact with client lab personnel
• Maintaining a detailed lab notebook
• Maintains and communicates inventory of laboratory supplies and equipment.

Technical

• Preparing samples for proteomic analysis by following a variety of established technical procedures according to written protocols.

• May operating facility instrumentation including off-line HPLC fractionation systems, mass spectrometers, speed vacs, and related instrumentation
• Performing initial data analysis
• May assist in the modification, development, and implementation of cutting edge protocols for clinical proteomics
• Maintains and stores cell lines and primary cultures.
• Maintains and stores test materials and products.

• Assisting facility staff and collaborators with results dissemination.

Qualifications

• Knowledge of tandem mass spectrometry and reversed phase chromatography (HPLC and nanoLC)
• Experience in the handling of cells, tissues, and/or clinical samples
• Practical experience with liquid chromatography, mass spectrometry instrumentation, proteomics sample preparation an asset

The applicant is expected to have a level of education, training, and experience equivalent to a BSc + 2 years of experience in an appropriate discipline or similar.

Benefits

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, which includes statutory benefits - Canada Pension Plan, Employment Insurance and WorkSafe BC plus the BC Cancer group benefits plan which includes medical & dental extended health, and group life insurance coverage, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type

Temporary renewable, Full-Time, 7.5 hrs. per day

100% onsite

Salary Range

$57,347 to $75,268

The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. 

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RA2_R00004_Proteomics_2024_06_03 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.